Recombinant Human Activating signal cointegrator 1 complex subunit 3 (ASCC3), partial from MyBioSource.com

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Recombinant Human Activating signal cointegrator 1 complex subunit 3 (ASCC3), partial

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Description

3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation